As a citizen of Sanctuary you reside within The Machine.
What is The Machine?
There seem to be many answers, but even more mysteries involved with this question.
If you have knowledge of The Machine, seek knowledge of The Machine, or wish to aid those who research The Machine and all of its many parts The Machinist Guild is the organization you have been seeking.
Come and join others of similar mind to further research and explore The Machine.
Contact Ichabod the Cripple at The Last Stand.