I know people are probably sick of diseases.. but there are some interesting diseases out there that could be done.
Blinding Sickness Spread in tainted water. (you go blind another nasty one)
Cackle Fever Symptoms include high fever, disorientation, and frequent bouts of hideous laughter. Also known as “the shrieks.” (possibly cause uncontrollable laughing emotes from time to time)
Demon Fever Night hags spread it. Can cause permanent ability drain. (not likely to be spread, and I wouldnt put permanent on it)
Devil Chills Barbazu and pit fiends spread it. It takes three, not two, successful saves in a row to recover from devil chills.
Filth Fever Dire rats and otyughs spread it. Those injured while in filthy surroundings might also catch it. (probably the most common one for filthy lower sanctuary and sewers)
Mindfire Feels like your brain is burning. Causes stupor. (uncontrollable stupor animation (poisoned emote))
Mummy Rot Spread by mummies. Successful saving throws do not allow the character to recover (though they do prevent damage normally). (( flies))
Red Ache Skin turns red, bloated, and warm to the touch.
The Shakes Causes involuntary twitches, tremors, and fits. (involuntary spazm emotes would be perfect here)
Slimy Doom Victim turns into infectious goo from the inside out. Can cause permanent ability drain (very nasty, may cause disease cone from time to time (probably when stat drop happens), aka vomit rat)
http://www.d20srd.org/srd/specialAbilities.htm